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A new Cobalamin-coated insulin-containing nanoparticleformulation delivered orally provided a pharmacological response (lowering ofblood glucose levels in an animal model of diabetes) equivalent to 90% of thatachieved by insulin delivered subcutaneously martina mcbride album . This represents a substantialoral bioavailability, indicating that this formulation has potential forclinical development and ultimate commercialization martina macbride . Adaptation of thistechnology has provided a Cobalamin human growth hormone formulation that hasdemonstrated good efficacy, represented by more than 25% improvement in weightgain, when given orally in an established animal model martina . Access continues tomove both products towards clinical development, and plans to submit anadditional patent application to protect the improvements to the technology Martina McBride tickets .Cobalamin is Access’ proprietary technology based upon the use of vitamin B12for targeted delivery of drugs to disease sites and for oral drug delivery ofdrugs that otherwise have poor oral bioavailability martinamcbride . The Access development ofa Cobalamin human growth hormone formulation is sponsored with funding from amajor pharmaceutical company, and Access is in discussion with other companiesregarding the application of the Cobalamin technology to other actives Martina McBride concert tickets – cmt .

“The recent improvements we have made to the nanoparticle carrier systemsshould provide us with the ability to adapt the technology more readily toother actives, allowing us to move new formulations more rapidly to theclinic,” commented David P Nowotnik, Ph.D, Access’ Senior Vice President ofR&D . “There are numerous actives that cannot be delivered orally, and so it isnot surprising that large pharma is showing a lot of interest in the Cobalamintechnology.”About Access:Access Pharmaceuticals, Inc my valentine martina . is an emerging biopharmaceutical company thatdevelops and commercializes propriety products for the treatment andsupportive care of cancer patients martina anyway . Access’ products include ProLindac(TM),currently in Phase 2 clinical testing of patients with ovarian cancer, andMuGard(TM) for the management of patients with mucositis .

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